Discovery Research Programs
Nutrients, The Digestive Tract And Diabetes
Program Leader: Dr. Khosrow Adeli
The research program brings together investigators from a wide-variety of disciplines, including endocrinology, gastroenterology, metabolism, neurobiology, nutrition and physiology. Through the application of cell, molecular and whole organism approaches in animal models as well as in humans, researchers examine the mechanisms underlying obesity and type 2 diabetes, as well as possible nutritional and therapeutic approaches to treat these diseases. One intestinal hormone of particular interest to members of the research group is the nutrient-stimulated incretin, glucagon-like peptide-1, which has already been successfully introduced into the clinic for the treatment of type 2 diabetes and which is under investigation for use as an anti-obesity agent. Through integration of their research expertise, and in collaboration with the CFI “3D Centre for studies on Diet, the Digestive Tract and Disease”, members of the platform will further accelerate the progression of basic science discoveries to the application of these findings in patients with obesity and diabetes.
The BBDC co-hosted the first annual collaborative conference with the Joslin Diabetes Center in 2014. The one and a half day event which was held in Toronto focused on nutrients, the digestive tract and diabetes and brought together the two leading diabetes research centres in Canada and the United States to promote the exchange of innovative research ideas and collaboration.