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Advani, Andrew - BSc, MBChB(Hons), PhD, FRCP(UK)

University of Toronto Appointment(s): Associate Professor/Clinician Scientist, Department of Medicine, Division of Endocrinology and Metabolism

Other Appointment(s): Staff Physician, St. Michael's Hospital

Contact Information:

St. Michael's Hospital
61 Queen Street East, Room 6-151
Toronto, Ontario M5C 2T2

Phone: 416-864-6060 Ext: 8413
Email: advania@smh.toronto.on.ca
Websites: http://www.stmichaelshospital.com/research/profile.php?id=advani&

Diabetes Related Research Activities:

Despite current treatments, people with diabetes continue to be affected by the long-term consequences of the disease. These long-term consequences are called complications and they include eye disease, kidney disease, nerve disease and heart disease. Kidney disease due to diabetes is the most common cause of kidney failure requiring treatment with dialysis or kidney transplantation and people with kidney disease are much more likely to also suffer from heart disease. Our lab is committed to conducting research on the causes of kidney disease in diabetes and on the links between kidney disease and heart disease. Our major research strands are: 1) Epigenetic mechanisms and related post-translational modifications; 2) Endothelial dysfunction and endothelial-podocyte interactions; 3) Re-purposing of existing therapies and exploration of the glucose-independent effects of diabetes treatments. Through this research we aim to develop new and better treatments for diabetes to reduce the burden of the condition on the millions of people affected.

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