BBDC Newsletter
| BBDC NEWS | Vol. 10, No. 1 -- September 2009 |
|---|
UPCOMING EVENTS
RECENT ADVANCES IN BETA CELL BIOLOGY: SCIENTIFIC AND CLINICAL
IMPLICATIONS
Register today to take advantage of the
low advance registration fees.
The Banting & Best Diabetes Centre is hosting
this official academic satellite symposium of the International Diabetes
Federation's 20th World Diabetes Congress
will be held October 16-17, 2009 at the Sheraton Centre Toronto Hotel.
The symposium will highlight very recent advances in our understanding of
beta cell biology with a focus on translational relevance and implications for
the treatment of both type 1 and type 2 diabetes.
The program will include guest speakers Drs. Susan Bonner-Weir, Peter
Butler, Marc Donath, Yuval Dor, Ele Ferrannini, Leif Groop, Andrew Hattersley,
Kevan Herold, Steven Kahn, Michael Nauck, Constantin Polychronakos, Guy Rutter,
Frans Schuit, and Susumu Seino, as well as poster and oral abstract
presentations. The complete program
and registration information is available on the symposium web site at
www.betacell2009.ca.
BBDC SEMINAR SERIES
The BBDC will be hosting diabetes-related seminars which are held in conjunction
with City-wide Endocrine Rounds. The seminars are held on selected Friday
mornings from 8 to 9 a.m. at the Mount Sinai Hospital,
Lebovic Building, 60 Murray Street, 3rd floor conference room.
Faculty wishing to meet with any of the visiting
speakers should contact the BBDC at
diabetes.bbdc@utoronto.ca .
Speakers will include:
3RD
Annual university of Toronto Symposium on Incretin Biology – 2009
This event will be held on Friday, November 27, 2009 at the MaRS Centre, 101 College Street, Toronto. Speakers will include Drs. Patricia Brubaker, Fiona Gribble, Klaus Kaestner, and Timothy Kieffer. For the complete program and registration details, please see the symposium website at http://contact.mshri.on.ca/registration/NSoIB2009/ . For more information contact Donna Doherty at 416-361-2661 or doherty@lunenfeld.ca .
FUNDING OPPORTUNITIES
IMPORTANT NOTICE: The
PILOT GRANTS FOR INNOVATIVE
ACTIVITIES RELATED TO DIABETES EDUCATION, MANAGEMENT AND CARE 2010/2011
This program provides funding of up to $10,000 per applicant for
pilot projects which are one to two years in length. It is
intended to support novel and innovative research initiatives in
the following general areas: i) Diabetes care delivery
ii) Evaluation of diabetes education programs iii)
Practical issues in diabetes management. This Pilot Grant program
is designed to encourage NEW academic research activities that would not
usually be supported by traditional granting processes.
Specifically, we invite applications from frontline diabetes health care
professionals working in University of Toronto affiliated institutions
or working with University of Toronto faculty. To be eligible, the
principal applicant must be a health care professional whose primary
appointment is with a University of Toronto affiliated institution or
with the University of Toronto. The principal applicant must be a
registered member* of the Banting and Best Diabetes Centre.
Staff at both fully and community affiliated University of Toronto
institutions are eligible to apply. Eligible applicants include
physicians, nurses, dietitians, pharmacists and others on the
front line of diabetes care. Those interested in submitting an
application must first submit a 1-page letter of intent and brief
estimated budget to the BBDC by September 29, 2009. For
complete award details and application instructions, please see the
following web page:
http://www.bbdc.org/fundingOpp/pilot.htm .
TRAINEE TRAVEL AWARDS 2009/2010 (PERIOD 1)
FOR TRAVEL OCCURRING BETWEEN JULY 1 AND DECEMBER 31, 2009
Awards of up to $1,000 (Canadian) are available to trainees who will be
traveling to a national or international meeting between July 1 and December 31,
2009 to present a first-author abstract. The content of the abstract must
be directly related to an area of diabetes research. To be eligible,
applicants must be registered graduate students, post-doctoral or clinical
fellows conducting diabetes research at the University of Toronto or one of its
affiliated institutions. The trainee’s supervisor must hold a full-time
faculty appointment with the University of Toronto and must also be a registered
member* of the BBDC at the time of
application submission. The
deadline for receipt of applications is 5 p.m., October 6, 2009.
For complete award details and application instructions please
see the following web page:
http://www.bbdc.org/fundingOpp/travel.htm .
REUBEN & HELENE DENNIS SCHOLAR IN DIABETES RESEARCH 2010-2012
This award is intended to support a new investigator in the early stage
of his/her career. The award provides $10,000/year for two years and is to
be used for diabetes research support and/or the salary of a clinician-scientist
conducting diabetes-related research. To be eligible, the applicant
must be a principal investigator who holds or will hold a full-time faculty
appointment at the University of Toronto as of July 1, 2010. Faculty are
eligible for this funding normally within five years of their first
faculty appointment at any university. The applicant must be conducting
diabetes-related research and must be a registered member* of the Banting and
Best Diabetes Centre, although membership is not required for those who do not
currently hold a U of T faculty appointment but expect to by July 1, 2010.
The deadline for receipt of applications is 5 p.m., October 27, 2009. For
complete award details and application instructions please see the following web
page:
http://www.bbdc.org/fundingOpp/dennis&new.htm .
DIABETES
EDUCATOR OF THE YEAR AWARD 2009
Each
year the BBDC presents one award to an individual who has demonstrated
outstanding efforts and achievements in his/her role as a diabetes educator.
This award is meant to recognize those who educate at the patient/client
and community/professional levels.
Candidates must be nominated for the award by a health care professional. To be
eligible, the nominee must be a
full-time or part-time diabetes educator or other health care
professional employed by a University of
Toronto-affiliated institution.
Educators
at both fully and community affiliated University of
Toronto institutions are eligible to be nominated.
The
nominee must have a minimum 3 years
of full-time or part-time
experience as a diabetes educator.
The deadline for receipt of nominations is Tuesday,
November 24, 2009.
For complete
award details and nomination instructions please see the following web page: http://www.bbdc.org/fundingOpp/educator.htm
.
Upcoming Funding
Opportunities:
- Charles Hollenberg Summer Studentship Program 2010 (application deadline January 2010)
- Annual Trainee Awards 2009/2010 (application deadline February 2010)
- Post-doctoral Fellowships 2010/2011 (application deadline February 2010)
* Those who are new to the field of diabetes research, education or care and are not members of the BBDC can request free membership by contacting the Centre prior to submitting an application. For more information about BBDC Membership, please view the MEMBERSHIP section of our web site at http://www.bbdc.org/membership/index.htm .
AWARD RESULTS**
gRADUATE AWARDS 2009/2010
| BBDC Graduate Studentships: |
||
|---|---|---|
| Student |
Supervisor(s) |
Title of Research |
|
Kevin Foley |
Dr. Amira Klip |
Cellular regulation of Na+-K+-ATPase traffic in response to insulin treatment
under normal and insulin resistant conditions. |
|
Hui Jun (June) Guo |
Dr. Adria Giacca |
Treatment of restenosis and atherosclerosis with insulin and insulin
sensitizers. |
|
Khajag Koulajian |
Dr. Adria Giacca |
Mechanisms of Oxidative Stress Mediated Beta Cell Glucotoxicity and Lipotoxicity
in Vivo |
|
Kimberly Kyle |
Dr. Marc Grynpas |
Comparative Analysis of the Effects of Pharmacological Inhibition vs Genetic
Ablation of DPP-4 Activity on Murine Bone Quality |
|
Michelle McFarlane |
Dr. Carol Westall |
Short-wavelength electroretingram (sERG) abnormalities in adolescents with Type
1 Diabetes and no clinically evident retinopathy |
|
Andrew Mulherin |
Dr. Patricia Brubaker |
Mechanism of action of metformin to stimulate GLP-1 secretion |
|
Monika Poreba |
Dr. Patricia Brubaker |
Role of CD36 in the stimulatory effects of fatty acids on glucagon-like
peptide-1 secretion |
|
Laura Sardone |
Dr. Marc Grynpas |
The Effect of Rosiglitazone Treatment on Bone Loss and Bone Quality in Rat
Models of Type 2 Diabetes and Osteoporosis |
|
Gavasker Sivaskandarajah |
Dr. Susan Quaggin |
The paradoxical role of angiogenesis and diabetic complications |
|
Stephanie Tung |
Dr. Denise Belsham |
Glucose sensing neurons: Regulation of Neuropeptide Synthesis by Glucose |
| BBDC-University Health Network Graduate Awards: |
||
|---|---|---|
| Student | Supervisor(s) |
Title of Research |
|
Safina Ali |
Dr. Daniel Drucker |
Role of the GLP-1 receptor in the metabolic phenotype of the Gcgr-/- mice |
| Wing Chee (Grace) Cheung |
Dr. Tony Lam |
Mechanisms of Small Intestinal CCK Signaling |
|
Joshua Columbus |
Dr. Tianru Jin |
Expression and Function of TCFs in Pancreatic and Intestinal Endocrine Cells |
| Andrea Kokorovic |
Dr. Tony Lam |
Mechanisms of small intestinal nutrient sensing |
|
Ying Kwan Aaron Ming |
Dr. Jonathan Rocheleau |
Revealing the mechanism behind glucose modulated beta-cell coupling in
pancreatic islets |
|
Anu Shah |
Dr. I. George Fantus |
The role of TxNIP in the development of ROS in presence of high glucose,
Angiotensin II, and/or TGF-β |
|
Madura Siva |
Dr. Allen Volchuk |
Examining the role of homocysteine-inducible ER stress protein (Herp) in the ER
stress response of pancreatic beta cells |
|
Akansha Tiwari |
Dr. Allen Volchuk |
Role of SDF2L1 and protein O-mannosylation in pancreatic beta-cells |
POSTDOCTORAL FELLOWSHIPS 2009/2010
The BBDC Fellowships in Diabetes Care have been made possible
by a $100,000 contribution from Eli Lilly Canada as well as the efforts
of and cooperation from the University Health Network. We are
grateful to both Eli Lilly Canada and the University Health Network for
their generous support.
| Applicant |
Supervisor(s) |
Title of Research |
Award |
|---|---|---|---|
|
Weijuan Shao |
Dr. Tianru Jin |
Role of crosstalk between insulin and Wnt signaling pathways in GLP-1 production |
BBDC Fellowship in Diabetes Care |
|
Dongzhe Song |
Dr. Gary Lewis |
Effects of CB1 receptor modulation on whole body and tissue specific insulin sensitivity |
BBDC Postdoctoral Fellowship |
|
Yi Sun |
Dr. Amira Klip |
Crossover of Two Signalling Pathways in Insulin Action:
The Missing Link Regulating GLUT4? |
BBDC Fellowship in Diabetes Care |
|
Ravi Vellanki |
Dr. Allen Volchuk |
The Role of OASIS in Endoplasmic Reticulum Stress Signaling in Pancreatic Beta Cells. |
BBDC Fellowship in Diabetes Care |
|
Dan Zhu |
Dr. Herbert Gaisano |
Rescuing insulin exocytotic deficiency in Type 2 diabetes |
BBDC Postdoctoral Fellowship |
** An essential condition of all BBDC programs is the acknowledgement of BBDC support, where appropriate, in all publications relevant to the BBDC-supported research program. Failure to appropriately acknowledge the BBDC’s support in relevant publications will be considered grounds for suspending future eligibility for BBDC funding programs.
BBDC CORE LABORATORY
The BBDC Core Laboratory provides analytical and technical support to
the
BBDC News is published in September, December, March and June of each year.
Current and past issues are available on our web site.
DIRECTOR: DANIEL J. DRUCKER, MD, FRCPC
Banting and Best Diabetes Centre
Faculty of Medicine, University of Toronto
Located at the Toronto General Hospital
200 Elizabeth Street
Eaton Building, 12th Floor, Room 12E248
Toronto, Ontario M5G 2C4
Phone: (416) 978-4656 • Fax: (416) 978-4108
E-mail:
diabetes.bbdc@utoronto.ca • Website:
www.bbdc.org