Research at the University
Profiles of BBDC Members involved in diabetes related research (A - L):
| On this page: A B C D E F G H I J K L | View M to Z
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A
Adeli, Khosrow,
PhD, FCACB, DABCC, FACB
Professor, Department of Biochemistry; and Department of Laboratory Medicine & Pathobiology,
University of Toronto
Division Head, Clinical Biochemistry, The Hospital For Sick Children
| Address: | The Hospital for Sick Children 555 University Avenue, Room 3652 Atrium Toronto, Ontario M5G 1X8 |
|---|---|
| Phone/FAX: E-mail: Web site: |
Phone: 416-813-8682 FAX: 416-813-6257 Khosrow.adeli@sickkids.ca http://www.sickkids.ca/Research/Adeli-Lab/index.html |
| Research Interests: | Lipid and Lipoprotein Disorders in Insulin Resistant States, Metabolic Syndrome and Type 2 Diabetes; Incretin Regulation of Intestinal Lipid and Lipoprotein Metabolism. Current areas of interest and active research in our laboratory include: Mechanistic studies of the link between diabetes and the increased risk of cardiovascular disease; Mechanisms of metabolic dyslipidemia in insulin resistant states; Regulation of Intestinal Lipid and Lipoprotein Metabolism by Gut Peptides; GLP-1 and GLP-2 signaling in the intesteine; Molecular biology of atherogenic lipoproteins and apolipoprotein B and involvement in the development of atherosclerosis; Mechanistic links between childhood obesity, insulin resistance, and the risk of development of premature atherosclerosis; mechanisms of action of hypolipidemic drugs at the cellular and molecular level. |
| Publications: |
|
Advani, Andrew,
BSc, MBChB(Hons), FRCP(UK), PhD
Assistant Professor/Clinician Scientist, Division of Endocrinology and
Metabolism, University of Toronto
Staff Physician,
St. Michael's Hospital
| Address: | St. Michael's Hospital 61 Queen Street East, Room 6-151 Toronto, Ontario M5C 2T2 |
|---|---|
| Phone/FAX: E-mail: Web site: |
Phone: 416-864-6060 Ext. 8413
FAX: 416-867-3696 advania@smh.toronto.on.ca http://www.stmichaelshospital.com/research/profile.php?id=advani& |
| Research Interests: | My research interests relate to the molecular pathobiology of diabetic complications and in particular kidney disease in diabetes. Diabetic nephropathy is the commonest cause of kidney failure in Canada. Our laboratory is committed to finding new treatments to slow or even reverse the progression of kidney disease. Our research is truly translational, studying the cellular processes involved in the development of the cardiovascular complications of diabetes and investigating the action of novel therapies both in vitro and in vivo. Through this, we hope to bring new treatments directly from the bench to the bedside. My research is focused on the critical role of high blood pressure in the progression of kidney disease and I am studying new ways to stimulate endothelial regeneration, the repair of the small blood vessels, damaged due to diabetes. Clinically, I have an interest in all aspects of diabetes care especially diabetes complications and diabetes ion young adults. |
| Publications: |
|
Azad, Azar, PhD
Lecturer, Department of Laboratory Medicine & Pathobiology,
University of Toronto
Manager, Banting & Best Diabetes Centre Core Laboratory
| Address: | Mount Sinai Hospital 600 University Avenue, 6th floor Toronto, Ontario M5G 1X5 |
|---|---|
| Phone/FAX: E-mail: |
Phone: 416-586-8545
FAX:
416-586-5950 aazad@mtsinai.on.ca |
| Research Interests: | |
| Publications: |
B
Bazinet, Richard P., PhD
Assistant Professor, Department of Nutritional Sciences, University of
Toronto
| Address: | FitzGerald Building 150 College St. , Room 306 Toronto , Ontario M5S 3E2 |
|---|---|
| PhoneFAX: E-mail: Web site: |
Phone: 416-946-8276 FAX:
416-978-5882 richard.bazinet@utoronto.ca www.utoronto.ca/nutrisci/faculty/Bazinet/ |
| Research Interests: |
1) Regulation of tissue uptake
and metabolism/signaling properties of fatty acids,
especially within the brain. 2) Genetic and dietary regulation of plasma fatty acid concentrations. |
| Publications: |
Belsham, Denise, PhD
Canada Research Chair in Neuroendocrinology,
CFI Researcher, University of Toronto
Professor, Departments of
Physiology, Medicine, and Obstetrics/Gynecology, University of Toronto
Affiliate Scientist, Division of Cellular & Molecular Biology, Toronto
General Research Institute, University Health Network
| Address: | University of Toronto, Medical Sciences
Building 1 King's College Circle, Room 3344C Toronto, Ontario M5S 1A8 |
|---|---|
| Phone/FAX: E-mail: Web sites: |
Phone: 416-946-7646 FAX:
416-978-4940 d.belsham@utoronto.ca http://www.physiology.utoronto.ca/res/list/belsham.htm http://www.uhnresearch.ca/researchers/profile.php?lookup=428 |
| Research Interests: | Obesity is a major global health concern and is a major risk factor for other disorders, including diabetes, hypertension, and heart disease. A complex neuronal system has evolved to maintain energy homeostasis, and also glucose homeostasis. Leptin, ghrelin, glucose, glucagon-like peptides, and insulin are known peripheral signals that act to regulate feeding and energy balance by modulating the expression of neuropeptides in the brain, specifically the hypothalamus. The afferent hormones leptin and insulin have common physiological responses and intracellular signaling mechanisms, but insulin resistance and leptin resistance are major metabolic problems, sometimes leading to type 2 diabetes. We have a strong track record of neuroendocrine research, focussing on molecular and cellular biology using hypothalamic neuronal cell models. Our research program includes studies of the regulation and signalling mechanisms in many of the neuropeptide-expressing neurons involved in energy homeostasis, and the molecular/cellular events leading to leptin/insulin resistance. Importantly, there is also a direct relationship between nutritional status and reproduction, another long-term interest of my laboratory, therefore my research program is poised to utilize all the information gained from our work to provide insight into the complex nature of integrated neuroendocrine control of basic physiology. |
| Publications: |
|
Bendeck, Michelle P.,
PhD
Professor, Department of Laboratory Medicine and Pathobiology,
University of Toronto
Career Investigator, Heart and Stroke Foundation of Ontario
| Address: | Department of
Laboratory Medicine and Pathobiology Medical Sciences Building, Room 6213 1 King's College Circle Toronto, Ontario M5S 1A8 |
|---|---|
| Phone: E-mail: |
416-946-7133 michelle.bendeck@utoronto.ca |
| Research Interests: | The main focus of research in my lab is on atherosclerosis and specifically on interactions between cells and extracellular matrix during vascular remodeling. We are investigating mechanisms of vessel wall thickening and remodeling using experimental models of arterial injury in mouse, rat and rabbit, studying the role of extracellular matrix, cell-surface integrin receptors, the novel discoidin-domain receptors and MMPs in mediating SMC responses. In collaboration with Dr. Adria Giacca, we are studying the effect of high glucose and insulin on SMC growth and matrix remodeling in atherosclerosis. |
| Publications: |
|
Bolz, Steffen-Sebastian,
MD, PhD
Associate Professor and Associate Chair, Research, Department of
Physiology, University of Toronto
| Address: | Medical Sciences Building, Room 3326 1 King's College Circle Toronto, ON M5S 1A8 |
|---|---|
| Phone/FAX: E-mail: |
Phone: 416-978-7529 FAX:
416-978-4373
sts.bolz@utoronto.ca |
| Research Interests: | My laboratory group recently started two projects that are related to diabetes: 1) The first project aims to understand the molecular signalling that underlies diabetes-associated microvascular structural and functional changes. Our special focus herein is on the role of microvascular sphingosine-1-phosphate signalling. 2) The second project aims to understand how heart failure affects the signalling network that ultimately controls blood glucose homeostasis. The special focus here is on the effects of TNFalpha on insulin and GLP-1 secretion. |
| Publications: |
|
Booth, Gillian L., MD, FRCPC
Associate Professor, Department of Medicine,
Division of Endocrinology & Metabolism; and
Department of Health Policy,
Management and Evaluation, University of Toronto
| Address: | Centre for Research on Inner City Health Li Ka Shing Knowledge Institute St. Michael's Hospital 209 Victoria Street Toronto, Ontario M5B 1T8 |
|---|---|
| Phone/FAX: E-mail: |
Phone: 416-864-6060 Ext. 77448 FAX:
416-864-3025 boothg@smh.ca |
| Research Interests: | My research focuses on health outcomes and quality of care related to diabetes. Specific interests include: 1) how neighbourhood characteristics (e.g. community design, the food environment) contribute to the prevalence of obesity and diabetes; 2) gender, socioeconomic, and regional differences in diabetes outcomes; 3) health care strategies to improve the quality of diabetes care and 4) the application of geographic analytic tools to health care planning. Much of this work is done using linkage of large secondary databases including provincial administrative health care data, population-based surveys and census, retail and other environmental data sources. Students and research fellows use epidemiological and health services research methods to study diabetes and its outcomes at a population-level. |
| Publications: |
|
Brubaker, Patricia L.,
PhD
Professor, Departments of Physiology and Medicine;
Staff Scientist, Division of Endocrinology & Metabolism, University of
Toronto
| Address: | University of Toronto,
1 King's College Circle Medical Sciences Building, Room 3366 Toronto, Ontario M5S 1A8 |
|---|---|
| Phone/FAX: E-mail: Web site: |
Phone: 416-978-2593 FAX:
416-978-2593 p.brubaker@utoronto.ca http://www.physiology.utoronto.ca/res/list/brubaker.htm |
| Research Interests: |
The major interests of the Brubaker laboratory relate to the synthesis, secretion and biological activities of gut hormones and, in particular, the intestinal glucagon-like peptides, GLP-1 and GLP-2. These hormones play important roles in the regulation insulin and glucagon secretion, beta cell proliferation, intestinal growth and function, and food intake. GLP-1 mimetics have recently been approved for the treatment of patients with Type 2 diabetes, while phase III clinical trials have recently been completed for the use of GLP-2 in the treatment of patients with intestinal insufficiency. Some of the areas that are currently under investigation in the lab include: 1) Regulation of GLP-1 and GLP-2 synthesis and secretion by
the intestine, with particular focus on dietary nutrients
and intracellular signalling pathways; and Students and fellows utilize a wide-variety of approaches to investigate the physiology and pathophysiology of the glucagon-like peptides, including normal and genetically-modified animals, cell culture and imaging approaches, in combination with tissue and cellular analyses at the mRNA and protein level |
| Publications: |
|
C
Carlen, Peter, MD,
FRCPC
Professor, Department of Medicine, Division of
Neurology, University of Toronto
Professor, Departments of Physiology, and IBBME, University of Toronto
| Address: | Toronto Western Research Institute 399 Bathurst St., Room 12-413 Toronto, Ontario M5T 2S8 |
|---|---|
| Phone/FAX: E-mail: |
Phone: 416-603-5017
FAX: 416-603-5768 carlen@uhnresearch.ca |
| Research Interests: | Main interests are mechanisms of neural synchrony and entrainment (epilepsy),
hypoglycemic seizures, and neurodegenerative processes. |
| Publications: |
|
Cherney, David,
MD, PhD, FRCPC
Assistant Professor, Department of Medicine,
Division of Nephrology, University
of Toronto
Clinician Scientist, University Health Network
| Address: | University Health Network 585 University Ave, 8N-845 Toronto |
|---|---|
| Phone/FAX: E-mail: |
416-340-4151 FAX:
416-340-4999 |
| Research Interests: | Current research interests in type 1 diabetes mellitus include the physiology of renal hyperfiltration in diabetic nephropathy, cardiorenal interactions and endothelial function, the effect of pharmaceutical agents on the urinary proteome, and functional gene polymorphisms in humans. |
| Publications: |
|
Colton, Patricia, MD
Assistant Professor, Department of Psychiatry, University of Toronto
| Address: | Toronto General Hospital 200 Elizabeth St., 7 Eaton South Rm. 409 Toronto, Ontario M5G 2C4 |
|---|---|
| Phone/FAX: E-mail: |
416-340-3477 FAX:
416-340-3430 patricia.colton@uhn.on.ca |
| Research Interests: | I am engaged in research related to psychosocial adjustment to diabetes, particularly risk for eating disorders and depression. I collaborate with Dr. Denis Daneman at Hospital for Sick Children, and we are conducting a longitudinal study of eating disturbances, depression, psychosocial functioning and medical status in girls and women with type 1 diabetes. |
| Publications: |
Connelly, Philip W.,
PhD
Associate Professor, Department of Medicine; and
Department of Laboratory
Medicine and Pathobiology, University of Toronto
Scientist, Keenan Research Centre, Li Ka Shing Knowledge Institute, St.
Michael's Hospital
| Address: | Room 5-029, Shuter Wing 30 Bond Street Toronto, ON M5B 1W8 |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-864-6023 FAX:
416-864-5870 connellyp@smh.ca St. Michael's Hospital web site profile |
| Research Interests: | The research interests of the laboratory are in the study of patients at risk for Type 2 Diabetes or at risk for the complications of diabetes and identifying serum biomarkers that will predict patient outcomes. The most recent focus has been on the adipokine adiponectin and on the enzyme paraoxonase-1 (PON1). Adiponectin is an insulin-sensitizing protein produced by adipocytes. PON1 is an anti-inflammatory component of high density lipoproteins. We have studied these factors in four patient groups: 1) The Sandy Lake Oji-Cree; 2) women at risk for post-gestational diabetes; 3) patients with renal failure on dialysis; and 4) renal transplant recipients. |
| Publications: |
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Cummins, Carolyn L., PhD
Assistant Professor, Faculty of Pharmacy, University of Toronto
| Address: | 144 College Street, Room 1101
Toronto, Ontario M5S 3M2 |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-946-3466 FAX:
416-978-8511 Carolyn.Cummins@utoronto.ca http://phm.utoronto.ca/~cummins/ |
| Research Interests: | Several members of the nuclear hormone receptor superfamily have been implicated in protecting against diseases associated with the metabolic syndrome. For example, from data obtained using animal models, it appears the liver X receptors (LXRα and LXRβ) are protective against atherosclerosis, dyslipidemia, and diabetes. The current focus of the Cummins lab is on the study of these nuclear hormone receptors and their roles in regulating glucose metabolism. Recently, we have shown that LXR is involved in the regulation of cholesterol conversion to glucocorticoids in the adrenal gland and are investigating the influence of this finding on glucose metabolism and the onset of type 2 diabetes. We are also exploring the link between LXR and the deposition of cholesterol in the glomeruli of the kidney in diabetic nephropathy. |
| Publications: |
|
D
Danska, Jayne
Professor, Department
of Immunology; Department of Medical Biophysics, University of
Toronto
Program in Genetics and Genome Biology, Hospital for Sick
Children
| Address: | MaRS, East Tower 101 College Street, Room 14-313 Toronto, Ontario M5G 1L7 |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-813-8810 FAX:
416-813-8823 jayne.danska@sickkids.ca http://www.sickkids.ca/Research/Danska-lab/index.html |
| Research Interests: | The objective of our research program is to define the genetic and environmental factors driving autoimmune mediated targeting of islet cells and to use this information to design and test therapeutics that prevent, block progression of or reverse type 1 diabetes. We have taken a multidisciplinary approach to genetic, genomic and immunological analysis of T1D risk in a well-validated mouse models, focusing on dissection of the complex genetics to provide insight into human T1D pathogenesis. We have extended these studies of the role of sex and of intestinal commensal bacteria on modifying genetic risk, and application of discoveries in rodent models to large, prospective cohort study of environmental determinants of T1D in genetically at risk children. |
| Publications: |
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De Melo, Margaret, BSc, RD, CDE
Professional Practice Leader-Clinical Nutrition, Allied Health
University Health Network
| Address: | Toronto Western
Hospital 399 Bathurst Street, 1WW-443 Toronto, Ontario M5T 2S8 |
|---|---|
| Phone/FAX: E-mail: |
416-603-5800 Ext. 5973
FAX: 416-603-5210 margaret.demelo@uhn.on.ca |
| Research Interests: | I am interested in research that focuses on diabetes self-care management (DSM). As part of interprofessional research teams, I have studied the effectiveness of DSM education programs, utilization and attrition such programs, food insecurity in Canadians with diabetes, and gender differences, psychosocial and clinical factors that help us better understand and serve those affected by diabetes. |
| Publications: |
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Dhe-Paganon, Sirano, PhD
Assistant Professor, Department of Physiology, University of Toronto
Principal
Investigator, Structural Genomics Consortium
| Address: |
101 College Street Toronto |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-946-3876 FAX:
416-946-0588 sirano.dhepaganon@utoronto.ca Lab web site |
| Research Interests: | We are using genomic enzymology to fill a gap between the science of proteins implicated in diabetes and the development of therapeutic molecules for use in the clinic. By understanding how proteins function at a molecular level, we provide insights into novel strategies for drug discovery and development. Studying paralogous targets allows us to tackle the issues of biological specificity and facilitate the development of potent therapeutics. Particularly, we are studying the ubiquitylation system, an emerging field implicated in metabolic diseases. |
| Publications: |
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Drucker, Daniel J., MD, FRCPC
Professor, Department of Medicine, Division of Endocrinology &
Metabolism, University of Toronto
Senior Scientist, Samuel Lunenfeld Research Institute, Mount Sinai
Hospital
| Address: | Mount Sinai Hospital, Samuel Lunenfeld
Research Institute 600 University Ave., TCP5-1004 Toronto, Ontario, M5G 1X5 |
|---|---|
| Phone/FAX: E-mail: Web sites: |
416-361-2661 FAX: 416-361-2669
drucker@lunenfeld.ca www.glucagon.com and www.mythyroid.com |
| Research Interests: | Research in the Drucker lab is focused on understanding the biology of gut hormones, with a major focus on GIP and the glucagon-like peptides. The lab studies how glucagon, GLP-1, and GLP-2 regulate energy homeostasis, metabolic control, and cardiovascular function via effects on the gastrointestinal tract, pancreas, cardiovascular system and central nervous system. Specific projects include physiological analyses of GIP, GLP-1, GLP-2 action, and elucidation of the functional control of glucagon, GIP, GLP-1 and GLP-2 action through studies of their respective receptors in peripheral tissues. Students and research fellows utilize a combination of techniques that involve studies of signal transduction, generation of transgenic or knockout mice, and studies of rodent models of glucagon-like peptide action with a focus on diabetes, obesity, endocrine systems, and intestinal disease. |
| Publications: |
|
E
El-Sohemy, Ahmed,
PhD
Associate Professor and Canada Research Chair in Nutrigenomics
Department of Nutritional Sciences, Faculty of Medicine, University of
Toronto
| Address: | 150 College Street, Room 350 Toronto, Ontario M5S 3E2 |
|---|---|
| Phone/FAX: E-mail: |
416-946-5776 FAX: 416-978-5882 a.el.sohemy@utoronto.ca |
| Research Interests: | The overall goal of my research program in nutrigenomics is to elucidate the genetic basis for variability in dietary response on cardiometabolic disease. We are also interested in identifying the genetic determinants of and dietary preferences and eating behaviours as they relate to obesity and type 2 diabetes. Our research program employs metabolomics, proteomics and genomics to study the effects of diet on human health. This approach will help us to understand how genetic and dietary factors interact to regulate various metabolic and biochemical pathways involved in the development of chronic diseases, such as type 2 diabetes. We are currently investigating the role of genetic polymorphisms affecting innate immunity and inflammation on components of the metabolic syndrome. Other research projects focus on identifying the genes influencing sugar and carbohydrate consumption in lean and obese individuals. |
| Publications: |
|
F
Fantus, I. George, MD, FRCPC
Professor, Department of Medicine; and Department of Physiology,
University of Toronto
| Address: | Mount Sinai Hospital 60 Murray Street Lebovic Toronto, Ontario M5T 3L9 |
|---|---|
| Phone/FAX: E-mail: |
416-586-8665 FAX:
416-361-2657 gfantus@mtsinai.on.ca |
| Research Interests: | The major research focus of our lab is to define the mechanisms of insulin resistance at the cellular and molecular level. The goal is to develop new approaches to treatment and prevention of insulin resistance. Studies in insulin target tissues, adipocytes and muscle cells, rendered insulin resistant by metabolites, e.g. glucose and free fatty acids; cytokines, e.g TNF-a; and hormones, e.g. insulin and angiotension, are carried out to determine changes in enzyme activation, in protein-protein interactions and glucose transporter translocation. The lab is also conducting research to define the abnormalities of cell signaling caused by exposure to high glucose. The goal here is to define the pathogenetic changes contributing to diabetic nephropathy. Studies in mesangial cells and in diabetic rodent models are addressing novel mechanisms by which alterations in the hexosamine biosynthesis pathway, oxidative stress, and cell signaling cause high glucose-mediated changes which trigger diabetic nephropathy. |
| Publications: |
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Farkouh, Michael E.,
MD, FRCPC, FACC, FAHA
Director, Clinical Trials, Peter Munk Cardiac Centre, University Health
Network
Director, Cardiology Research, Division of Cardiology, University of
Toronto
Associate Professor, Department of Medicine, University of Toronto
Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
| Address: | Peter Munk Cardiac Centre, University Health Network 585 University Avenue, Room 4N474 Toronto, Ontario M5G 2N2 |
|---|---|
| Phone/FAX: E-mail: |
416-340-3141 FAX:
416-340-3398 Michael.farkouh@uhn.ca |
| Research Interests: | Diabetes Mellitus and Cardiovascular Disease: The main focus is the evaluation of diabetic patients with coronary artery disease, acute coronary syndromes and heart failure. We have examined the role of advanced multi-modal imaging in developing novel compounds to treat atherosclerosis in diabetic patients. I have conducted large-scale clinical trials such as the FREEDOM Trial which evaluated the optimal strategy required for the management of coronary artery disease. Our goal for the future is to develop a collaborative coordinating center to address the important clinical questions revolving around diabetes and heart disease. |
| Publications: |
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Feig, Denice S.,
MD, MSc, FRCPC
Associate Professor, Departments of Medicine, Obstetrics & Gynecology,
Health Policy, Management and Evaluation; Division of Endocrinology &
Metabolism, University of Toronto
| Address: | Mount Sinai Hospital 60 Murray St., Room 5027 Toronto, Ontario, M5T 3L9 |
|---|---|
| Phone/FAX: E-mail: |
Phone: 416-586-8590 FAX: 416-361-2657 dfeig@mtsinai.on.ca |
| Research Interests: | Main research interest is in the area of diabetes in pregnancy. We are currently conducting a multi-centre randomized controlled trial of metformin use in women with type 2 diabetes in pregnancy (MiTy trial). I am also involved in studies looking at the placental transfer of diabetes drugs in pregnancy, the transfer of diabetes drugs into breast milk, and administrative databases looking at women with diabetes in pregnancy in Ontario. |
| Publications: |
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Floras, John S.,
MD, DPhil, FRCPC, FACC, FAHA, FESC
Professor, Department of Medicine, University Health Network and Mount
Sinai Hospital Division of Cardiology (Divisional Research Director),
University of Toronto
Canada Research Chair in Integrative Cardiovascular Biology
Chair, Board of Trustees, Banting Research Foundation
| Address: | Mount Sinai Hospital 600 University Avenue, Suite 1614 Toronto, ON M5G 1X5 |
|---|---|
| Phone/FAX: E-mail: |
416-586-8704 FAX:
416-586-8702 john.floras@utoronto.ca |
| Research Interests: | The general theme of the Floras Clinical Cardiovascular Physiology Laboratory has been the elucidation of mechanisms responsible for initiation and progression of cardiovascular and related diseases in humans, through interdisciplinary patient oriented research. Neural and intrinsic cardiovascular regulation is studied using: microneurographic recordings of sympathetic nerve discharge directed at resistance vessels, tracer kinetic methods to estimate total body norepinephrine spillover, spectral analysis of heart rate variability and baroreflex sensitivity for heart rate, plethysmographic methods for assessing blood flow, and ultrasonic methods for quantifying endothelium dependent and independent vasodilatation. These methods have been applied to research questions concerning normal health and aging, and to conditions such as heart failure, sleep apnea, hypertension, renal failure, pulmonary hypertension, diabetes (in collaboration with Drs. Zinman, Millar and Meneilly), menopause and cirrhosis. |
| Publications: |
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Fu, Lei, PhD,
DABCC, FACB, FCACB
Assistant Professor, Department of
Laboratory Medicine & Pathobiology, University of Toronto
Clinical Biochemist, Department of Clinical Pathology, Sunnybrook Health
Sciences Centre
| Address: | Department of Clinical Pathology Sunnybrook Health Sciences Centre Room B204, 2075 Bayview Avenue Toronto, Ontario M4N 3M5 |
|---|---|
| Phone/FAX: E-mail: |
416-480-6100 Ext. 89571 FAX:
416-480-6035 lei.fu@sunnybrook.ca |
| Research Interests: | To study the molecular relationship between vitamin D endocrine system and diabetes. |
| Publications: |
G
Gaisano, Herbert Y.,
MD, FRCPC, FACP
Professor, Departments of Medicine and
Physiology, University of Toronto
| Address: | University of Toronto, Medical Sciences
Building 1 King's College Circle, Rooms 7358 and 7368 Toronto, Ontario, M5S 1A8 |
|---|---|
| Phone • Fax: E-mail: |
416-978-1526 • Fax: 416-978-8765 herbert.gaisano@utoronto.ca |
| Research Interests: | Research in the Gaisano lab is focused on molecular mechanisms regulating exocytosis, employing islet cells as models. We were first to demonstrate that SNARE proteins originally found to mediate neurotransmitter release are conserved in non-neuronal cells to regulate secretion. We contributed much of the original work showing how SNARE proteins physically and functionally interact with beta-cell ion channels (Kv, KATP, Ca2+) to regulate the intricate sequence of ion fluxes, membrane potential and exocytotic fusion events leading to secretion. Current efforts are directed at: 1) SNARE proteins regulation of compound insulin exocytosis; 2) insulin granule priming and tethering; 3) islet alpha cell secretory mechanisms and crosstalk with beta-cells in health and diabetes; and 4) SNARE interactions with KATP and Kv channels in beta-cells and cardiac myocytes. This lab has in place full spectrum of functional assays for islet cells, including islet perifusion assays and single cell analyses (patch clamp electrophysiology, capacitance measurements, imaging of single granule exocytosis by TIRFM & multi-photon microscopy). This lab also has full capabilities to perform assays for in vivo glucose homeostasis (glucose clamps), islet cell biology (islet isolation, examining intact islets within pancreatic slices, E.M.), biochemistry (immunoprecipitation, FRET analysis), molecular biology and gene transfer (adenovirus construction). |
| Publications: |
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Ganguli, Rohan,
MD, FRCPC
Professor, Department of Psychiatry, University of Toronto
Canada Research Chair in Chronic Disease Management
Executive Vice President, Clinical Programs,
Center for Addiction and Mental Health
| Address: | Center for Addiction and Mental Health Toronto |
|---|---|
| Phone/FAX: E-mail: |
416-535-8501 Ext. 2102 FAX: - Rohan_Ganguli@camh.net |
| Research Interests: | I moved to Toronto from the |
| Publications: |
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Giacca, Adria
Professor, Department
of Physiology and Department of Medicine, University of Toronto
| Address: | University of Toronto, Medical Sciences
Building 1 King's College Circle, Room 3336 Toronto, Ontario M5S 1A8 |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-978-0167 FAX: 416-978-4373
adria.giacca@utoronto.ca http://www.physiology.utoronto.ca/res/list/giacca.htm |
| Research Interests: | The primary theme of A.G.'s research is the investigation of the effects of excess circulating energy substrates, in particular free fatty acids, on insulin action, secretion and kinetics, and the implication of these effects for the pathogenesis of diabetes. Secondary themes of research are the studies of the effects of nutrient and insulin excess on : i) the proliferation of normal and tumorous colonic epithelial cells; ii) vascular smooth muscle cell proliferation in vivo. |
| Publications: |
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Gilbert, Richard E.,
MD, PhD, FRCPC
Professor, Department of Medicine,
University of Toronto
Division of Endocrinology & Metabolism, St. Michael's Hospital
Canada Research Chair in Diabetes Complications
| Address: | Keenan Research Centre, Li Ka Shing Knowledge Institute
St. Michael's Hospital 209 Victoria Street, Room 5-08 Toronto, Ontario Canada M5B 1C6 |
|---|---|
| Phone: E-mail: Web site: |
416-867-3747 richard.gilbert@utoronto.ca http://www.stmichaelshospital.com/research |
| Research Interests: | Research in the Gilbert lab focuses on the pathogenesis of diabetes complications as a way to evolve new therapies to prevent their development and attenuate their progression. Current projects utilise animal models of diabetic nephropathy, retinopathy and heart failure, exploring novel epigenetic pharmacological treatments and the use of adult stem cells to regenerate diseased tissue. |
| Publications: |
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Glazier, Rick,
MD, MPH, FCFP
Professor, Department of
Family and Community Medicine, University of Toronto
Senior Scientist, Institute for Clinical Evaluative Sciences
Scientist, Centre for Research on Inner City Health, St. Michael’s
Hospital
| Address: | Centre for Research on Inner City Health St. Michael’s Hospital 30 Bond Street Toronto, ON M5B 1W8 |
|---|---|
| Phone: E-mail: |
416-864-6060 Ext. 77444 glazierr@smh.ca |
| Research Interests: |
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| Publications: |
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Glogauer, Michael,
DDS, PHD
Associate Professor, Faculty
of Dentistry; Faculty of Medicine, University of Toronto
Appointments: Hospital For Sick Children, Mount Sinai Hospital,
Sunnybrook Health Sciences Centre, and Toronto Rehab
| Address: | Room 221, Fitzgerald
Building 150 College Street Toronto, Ontario M5S 3E2 |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-978-0163 FAX: 416-978-5956
michael.glogauer@utoronto.ca http://matrixdynamics.ca |
| Research Interests: | Impact of diabetes on innate immunity and neutrophil functions. Impact of diabetes on oral health and periodontal diseases. Impact of diabetes on osteoimmunology. |
| Publications: |
Greenwood, Carol E.,
PhD
Professor,
Department of Nutritional Sciences, University of Toronto
| Address: | Baycrest Centre 3560 Bathurst Street Toronto, Ontario M6A 2E1 |
|---|---|
| Phone/FAX: E-mail: |
416-978-4261 FAX: 416-978-5882
carol.greenwood@utoronto.ca www.utoronto.ca/nutrisci/ and www.baycrest.org |
| Research Interests: | Research in the Greenwood lab is focused on understanding the effect of diet and metabolic disorders, including type 2 diabetes, on the retention or loss of cognitive function with aging. Our studies, in both humans and animal models, show that the consumption of diets which promote obesity and type 2 diabetes are associated with more rapid decline in cognitive function. By contrast, consumption of healthy diets associates with retention of cognitive function. Our current interest lies in understanding the adverse brain effects of type 2 diabetes. These studies draw on functional magnetic resonance imaging as a means of determining underlying neuronal pathways and neuronal responses which are impacted. |
| Publications: |
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Grynpas, Marc, PhD
Professor, Department of Laboratory
Medicine and Pathobiology, University of Toronto
Director, Bone and
Mineral Group, University of Toronto
| Address: | Mount Sinai Hospital 600 University Avenue, Suite 840 Toronto, Ontario, M5G 1X5 |
|---|---|
| Phone/FAX: E-mail: Web Site: |
416-586-4800 Ext:4464
FAX:
416-586-1554 Grynpas@lunenfeld.ca |
| Research Interests: | Our research focuses on the effects of diabetes on the
skeletal system using pre-clinical models. Examples of our research includes:
|
| Publications: | Kyle KA, Willett TL, Baggio LL, Drucker DJ, Grynpas MD. (2010) Differential effects of PPAR-gamma activation vs chemical or genetic reduction of DPP-4 activity on bone quality in mice. J of Endocrinology Feb, 2011 Vol.152, No.2 457-467 |
H
Halperin, Mitchell,
MD, FRCPC, FRS,
MD Honoris Causa, Univ. Montreal and Univ. d’Auvergne, France
Emeritus Professor, Faculty of Medicine, University of Toronto
Attending staff, Nephrology, St. Michael’s Hospital
Investigator Research Division, Li Ka Shing Knowledge Institute, St.
Michael’s Hospital
| Address: | St. Michael’s Hospital 30 Bond Street, Room 408 LSKI Toronto ON M5B1A8 |
|---|---|
| Phone/FAX: E-mail: |
Phone: 416-864-5292 FAX:
1-888-325-9302 Mitchell.halperin@utoronto.ca |
| Research Interests: | I am interested in seeking the causes of cerebral edema in patients with diabetic ketoacidosis (DKA) and the role of stomach emptying as an occult risk factor. |
| Publications: |
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Hamilton, Jill,
MD, FRCPC
Associate Professor, Department of Paediatrics,
Division of Endocrinology, University of Toronto
Associate Scientist, Physiology and Experimental Medicine, SickKids
Research Institute
| Address: | The Hospital For Sick Children, Division of
Endocrinology 555 University Avenue, Room 5447 Toronto, Ontario M5G 1X8T |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-813-5115 FAX: 416-813-6304
jill.hamilton@sickkids.ca www.obesityinyouth.org |
| Research Interests: | My research interests include the clinical and physiologic manifestations of
insulin resistance and pancreatic beta cell function in the pediatric age group.
Recent studies include: (i) risk for diabetes and metabolic syndrome and pathophysiologic mechanisms related to the development of hypothalamic obesity in children treated for craniopharyngioma; (ii) early life risk factors for the development of obesity and diabetes in infants born to women with gestational diabetes; (iii) incidence and clinical presentation of type 2 diabetes in Canadian children (iv) role of ectopic fat deposition and metabolic consequences in obese children and adolescents |
| Publications: |
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Hanley, Anthony,
PhD
Associate Professor, Department of Nutritional Sciences;
Department of Medicine;
and Dalla Lana School of Public Health, University of Toronto
Canada Research Chair in Diabetes Epidemiology
Associate Scientist, Leadership Sinai Centre for Diabetes, Mount Sinai
Hospital
| Address: | 150 College Street, FitzGerald Building,
Room 341 Toronto, Ontario M5S 3E2 |
|---|---|
| Phone/FAX: E-mail: |
416-978-3616 FAX: 416-978-5882 anthony.hanley@utoronto.ca |
| Research Interests: | Dr. Hanley’s research interests include the metabolic and nutritional epidemiology of type 2 diabetes and related disorders including obesity, insulin resistance, and beta cell dysfunction, as well as the micro-and macro-vascular complications of type 2 diabetes. His research focuses on diabetes in Aboriginal Canadian communities and other high-risk populations. Current projects include the Sandy Lake Health and Diabetes Project, the PROMISE study, as well as collaborations with the Insulin Resistance Atherosclerosis Study and the Gestational Diabetes and Acute Phase Biomarkers research groups. |
| Publications: |
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I
Irwin, David M.
Professor, Department of Laboratory Medicine and Pathobiology,
University of Toronto
| Address: | Medical Sciences Building,
Room 6207 1 King’s College Circle Toronto, Ontario M5S 1A8 |
|---|---|
| Phone: E-mail: Web Site: |
416-978-0519 david.irwin@utoronto.ca http://icarus.med.utoronto.ca/patho/faculty.asp?FacultyID=159 |
| Research Interests: | Research in the Irwin lab focuses on the evolution of genes
involved in diabetes. Many of the genes and proteins
(e.g., the proglucagon-derived peptides glucagon, GLP-1, and
GLP-2) involved in glucose metabolism are related yet have
differing function. By examining the origin and evolution
of these genes we hope to identify portions of the sequences
important for their unique functions. We are also interested in
role of liver-specific glucokinase in glucose metabolism.
We are currently using comparative and molecular approaches to identify regulatory sequences essential for regulation of expression, including insulin induction, of the glucokinase gene in the liver. |
| Publications: |
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J
Jenkins, David J. A.,
MD, PhD
Professor,
Departments of Medicine and Nutritional Sciences, Faculty of Medicine, University of Toronto
Director of Clinical Nutrition and Risk Factor Modification Centre, St.
Michael’s Hospital
| Address: | St. Michael’s Hospital Risk Factor Modification Centre
61 Queen Street East Toronto, Ontario M5C 2T2 |
|---|---|
| Phone/FAX: E-mail: |
416-867-7475
FAX: 416-867-7495
NutritionProject@smh.ca |
| Research Interests: | Dr. Jenkins research area is
the use of diet in the prevention and treatment of hyperlipidemia and diabetes.
He has over 200 original publications on these and related topics.
His team was the first to define and explore the concept of the glycemic
index of foods and demonstrate the breadth of metabolic effects of viscous
soluble fiber, including blood glucose and cholesterol lowering.
His studies on combining cholesterol lowering food components (dietary
portfolio) have been recognized as creating an effective dietary alternative to
drug therapy (statins) for many people and was the only dietary approach
referenced in the update of the guidelines of the US National Cholesterol
Education Program (ATP |
| Publications: |
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Jin, Tianru
Associate Professor,
Department of Medicine, Division of Endocrinology & Metabolism, University of Toronto
| Address: | MaRS Centre, Toronto Medical Discovery Tower 101 College Street, Room 10-354 Toronto, Ontario, M5G 1L7 |
|---|---|
| Phone: E-mail: |
416-581-7670 tianru.jin@utoronto.ca |
| Research Interests: |
A) Mechanisms Underlying the Production and Function of the Incretin Hormone
GLP-1. The proglucagon gene (Gcg) encodes three major peptide hormones, namely
glucagon (produced in pancreas), glucagon-like peptide-1 (GLP-1) and GLP-2 (both
are produced mainly in intestines). These hormones exert opposite or overlapping
functions in controlling blood homeostasis, food intake, cell growth and
proliferation. Based on the features of GLP-1, two new categories of drugs,
namely GLP-1 analogues and DPP-IV inhibitors, have been developed for T2D
treatment. We are exploring mechanisms underlying the production and function of
peptide hormones encoded by Gcg, including GLP-1. We are now studying the role
of Wnt signalling and the crosstalk between Wnt and other signalling pathways in
regulating the expression and function of GLP-1. B) Mechanisms Underlying the Expression and Function of the Lipogenic Gene Carbohydrates Response Element Binding Protein (ChREBP). The transcription factor ChREBP is a “master controller” of lipogenic genes that encode a battery of enzymes for converting carbohydrates into lipids. The function of ChREBP can be turned on by hyperglycemia and its expression was shown to be increased in obesity and hyperinsulinemia animal models. We are studying molecular mechanisms underlying the expression of ChREBP and its targets. |
| Publications: |
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Josse, Robert G., BSc,
MB, BS, FRCP, FRCPC, FACP, FACE
Professor of Medicine, University of Toronto
Division of Endocrinology and Metabolism, St. Michael's Hospital
| Address: | St. Michael's Hospital 61 Queen St. East, 6th Floor, Suite 6122 Toronto, Ontario M5C 2T2 |
|---|---|
| Phone/FAX: E-mail: |
416-867-7455 FAX:
416-867-3696 josser@smh.toronto.on.ca |
| Research Interests: | Often with an emphasis in clinical nutrition, I have obtained peer review and non peer review grants (mostly Phase II and III pharmaceutically funded multicentre national and international studies) as Principal, Co-principal or Co-investigator. These studies have investigated the effects of various new drugs on diabetes control, hyperlipidemia and prevention and treatment of diabetes complications. I have been particularly interested in the nutritional management of diabetes with other colleagues in the Department of Nutritional Sciences (Jenkins, Wolever). We have promulgated the concept of the glycemic index of foods and the importance of meal frequency as therapeutic principles. |
| Publications: |
K
Kilkenny, Dawn M.,
PhD
Assistant Professor, Institute of
| Address: | 164 College Street 407 Rosebrugh Toronto, ON M5S 3G9 |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-978-8835 FAX: 416-978-4317 dawn.kilkenny@utoronto.ca http://www.ibbme.utoronto.ca/Page359.aspx |
| Research Interests: | My research is focused on expression of Fibroblast Growth Factor receptors (FGFR) in adult beta cells. Signaling via members of this family of tyrosine kinase receptors is associated with beta cell maintenance and survival. We previously determined that both FGFR1-expression and -signaling are altered by beta-cell extracellular microenvironment. We are now investigating the role of the novel kinase-deficient FGFR5 isoform in the regulation of beta-cell FGFR1-signalling. FGFR5 was originally identified over a decade ago in pancreas and bone, however little is known about its function. Using insulin-secreting cell lines, we determined expression of FGFR5 both at the cell membrane as well as in association with insulin secretory granules. Expression of a ‘dominant-negative’ (kinase-deficient) isoform of classical FGFR1, which is similar in structure to FGFR5, has been shown to induce a diabetic phenotype in mice. Taken together, these data promote our interest in defining the role that FGFRs play in normal beta-cell maintenance and insulin secretion. We currently examine this receptor signaling system using methods of fluorescence microscopy (live-cell and fixed) both in vitro as well as in vivo (whole islet). Studies are verified in combination with traditional biochemical techniques. |
| Publications: | N/A |
Klip, Amira
Professor, Department
of Paediatrics; Department of Biochemistry; and Department of
Physiology, University of Toronto
Senior Scientist, The Hospital For Sick Children
| Address: | The Hospital for Sick Children McMaster Building, Room 5004 555 University Ave. Toronto, Ontario M5G 1X8 |
|---|---|
| Phone/FAX: E-mail: Web site: |
416-813-6392 FAX:
416-813-5028 amira@sickkids.ca The Hospital For Sick Children web site profile |
| Research Interests: | Our research explores how insulin stimulates glucose entry into muscle cells and how this fails in insulin resistance and type 2 diabetes. We explore insulin signals, movement of vesicles containing glucose transporter 4 (GLUT4) and strategies to render muscle cells insulin resistant. Using biochemical strategies, single cell imaging and proteomics, we discovered that GAPDH binds to GLUT4 in response to insulin and regulates the transporter activity. We also generated a transgenic mouse expressing a tagged version of GLUT4 in its muscles, useful to test GLUT4 movement in vivo. Recently we found that the saturated fatty acid palmitate renders macrophages (innate immunity cells) inflammatory, to produce cytokines that in turn make muscle cells resistant to insulin. The muscle cells respond by activating stress pathways and altering insulin signalling at the levels of the kinase Akt and the small G protein Rac. Rac controls actin filament remodelling, crucial for GLUT4 vesicle translocation. In 2010 we found that: 1. Rac activates both the complex Arp2/3 to cause actin filament branching and the actin severing protein cofilin, creating a dynamic cycle of actin filament branching and breaking that allows GLUT4 tethering near the membrane. 2. Downstream of Akt lies the protein AS160 that regulates the small G proteins Rab8A and Rab13, to control GLUT4 vesicle arrival near the membrane. 3. Direct activation of an innate immunity recognition receptor in the muscle cells, NOD2, causes insulin resistance. Collectively, these findings will help discover the underlying mechanism of insulin resistance during obesity and its related inflammation. |
| Publications: |
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L
Lam, Tony K. T.,
PhD
John Kitson McIvor Endowed Chair in Diabetes Research
Canada Research Chair in Obesity
Associate Director, Research, Banting & Best Diabetes Centre
Associate Professor, Departments of Physiology and Medicine, University
of Toronto
Scientist,
Toronto General Research Institute, University Health Network
| Address: | MaRS/Toronto Medical Discovery Tower 101 College Street, 10th Floor, Room 705 Toronto, Ontario M5G 1L7 |
|---|---|
| Phone/FAX: E-mail: Web sites: |
416-581-7880 FAX: 416-581-7880 tony.lam@uhnres.utoronto.ca Department of Physiology web site profile University Health Network web site profile |
| Research Interests: | Nutrient sensing in the Gut and the Brain, Diabetes, Obesity, Glucose and Lipid metabolism. |
| Publications: |
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Law, Marcus, MD,
MBA, CCFP
Assistant Professor, Department of Family &
Community Medicine, University of Toronto
Staff Physician; Postgraduate Family Medicine Site Director; and
Director of Medical Education, Toronto East General Hospital
| Address: | Family Health Centre 840 Coxwell Ave., Suite 105 Toronto, Ontario M4C 5T2 |
|---|---|
| Phone/FAX: E-mail: |
416-469-6580 Ext. 6545 FAX: 416-469-6108 marcus.law@utoronto.ca |
| Research Interests: | Health care provider education of diabetes management and innovation in delivery of primary care chronic disease management, especially diabetes, in an interprofessional setting. |
| Publications: |
Leiter, Lawrence,
MD, FRCPC, FACP
Professor, Department of Medicine;
and Department of Nutritional Sciences, University of Toronto
Division of Endocrinology & Metabolism, St. Michael’s Hospital
| Address: | St. Michael's Hospital 61 Queen St. East, Room 6121 Toronto, Ontario M5C 2T2 |
|---|---|
| Phone: E-mail: |
416-867-7441 leiterl@smh.ca |
| Research Interests: | Dr. Leiter has several research interests including clinical trials on the prevention of atherosclerosis, especially in diabetes, and the dietary and pharmacologic treatment of diabetes mellitus, hyperlipidemia, hypertension, and obesity. He was an investigator in many of the landmark diabetes trials including the DCCT, ACCORD, and ADVANCE and is on the Steering Committees of many ongoing outcome trials in both the diabetes and lipid areas. |
| Publications: |
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Leong-Poi, Howard,
MD, FRCPC, FASE
Associate Professor of Medicine, University
of Toronto
Clinician Scientist in the Keenan Research Centre at the Li Ka Shing
Knowledge Institute
Head, Division of Cardiology, St. Michael’s Hospital
Brazilian Ball Research Chair in Cardiology
| Address: | St. Michael's Hospital 30 Bond Street, 6-044 Queen Wing Toronto, Ontario, M5B 1W8 |
|---|---|
| Phone/FAX: E-mail: |
416-864-5642 FAX: 416-864-5989 Leong-PoiH@smh.ca |
| Research Interests: |
Research interests focus in several key areas:
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| Publications: |
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Lewis, Gary, MD,
FRCPC
Professor, Department of Medicine; and Department of Physiology,
University of Toronto
Director, Banting & Best Diabetes
Centre, University of Toronto
Director, Division of Endocrinology & Metabolism, University of
Toronto
Drucker Family Chair in Diabetes Research
| Address: | Office: Toronto General Hospital 200 Elizabeth St., Eaton Building, Room 12E244 Toronto, ON M5G 2C4 Lab: MaRS Centre, Toronto Medical Discovery Tower 101 College St., Room 10-203 Toronto, ON M5G 1L7 |
|---|---|
| Phone/FAX: E-mail: |
Office: 416-340-4270 Lab: 416-581-7487
FAX: 416-340-3314 gary.lewis@uhn.ca |
| Research Interests: | The Lewis lab performs whole body, integrative, physiological studies in humans.
The major line of research interest of Dr. Lewis' laboratory is: |
| Publications: |
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Lipscombe, Lorraine L.,
MD, MSc, FRCPC
Assistant Professor, Department of Medicine; Department of Health
Policy, Management and Evaluation, University of Toronto
Research Scientist, Women’s College Research Institute
Adjunct Scientist, Institute for Clinical Evaluative Sciences (ICES)
Staff Physician, Department of Medicine, Division of Endocrinology and
Metabolism, Women’s College Hospital
| Address: | Women’s College Research Institute 741 – 790 Bay Street Toronto, Ontario, M5G 1N8 |
|---|---|
| Phone/FAX: E-mail: Website: |
416-351-3732 Ext.3701
FAX: 416-351-3746 lorraine.lipscombe@wchospital.ca http://www.womensresearch.ca/people/faculty/lipscombe.php |
| Research Interests: | Dr. Lipscombe’s research program is aimed at improving the care and outcomes of persons living with diabetes with a particular focus on women, and targeting special female populations at higher risk for diabetes who would benefit from more focused diabetes prevention strategies. Her specific priority areas of interest include the association between breast cancer and diabetes, pregnancy planning in women with diabetes, post-partum diabetes risk and prevention in women with gestational diabetes, and drug safety in seniors with diabetes. |
| Publications: |
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Lowe, Julia,
MB.ChBFRCP (UK) M.Med.Sci
Associate Professor, Department of
Medicine, Division of Endocrinology & Metabolism, University of Toronto
| Address: | Sunnybrook Health Sciences Centre Room H145, 2075 Bayview Avenue Toronto, Ontario M4N 3M5 |
|---|---|
| Phone/FAX: E-mail: |
416-480-6948 FAX: 416-480-4250 julia.lowe@sunnybrook.ca |
| Research Interests: | I received broad training as a specialist general internal physician, as well as specialty training in endocrinology in the UK. After completing this I went to Australia where I worked 25 years, first in community practice and then as a staff physician at John Hunter Hospital one of the teaching hospitals for Newcastle Medical school. I have a Masters in clinical epidemiology. For 4 years I was the Area Director of Diabetes for the Hunter region of NSW. My research interests are in chronic diabetes in pregnancy and health care delivery for diabetes. My research projects included the HAPO study and the Australian Longitudinal Study in Women’s health, and a survey of Australian women with gestational diabetes. I also have funding for research into the epidemiology and use of health services by women with diabetes, and follow up of people who have attended diabetes and prediabetes education programmes in the Hunter and to redesign the service provided for young people with Type 1 diabetes in rural areas. In January 2008 I started work at the University of Toronto where I hold the rank of Associate Professor. Since coming to Toronto I have started a research programme on the management of diabetes in hospital inpatients and collaborated with colleagues in research on diabetes in pregnancy as well as continuing my Australian research. |
| Publications: |
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